Kratom: Chemistry

Kratom and ChemistryKratom has been a savior to many people, not just in the US but around the world. However, many people only have a general understanding of the plant and of how it works. It is important to have some common knowledge, but it can also be useful to know the plant’s exact chemistry.

Kratom’s properties begin with the alkaloids found within the leaves of the plant. The compounds of the plant interact with human cells and stimulate the sympathetic nervous system. There are about 40 known alkaloids in Kratom, the most important being mitragynine and 7-hydroxymitragynine in the highest concentrations. The chemical make-up of Mitragynine is C23H30N2O4. This alkaloid is soluble in alcohol solutions but not in water. 7-hydroxymitragynine, with the chemical name C23H30N2O5, works much in the same way as Mitragyne. Both of the alkaloids work within the body much like opioid’s, however, Kratom is not an opiate. How exactly these alkaloids work within the body is not known yet, but there is a major history of plant alkaloid use.

Some of the mental effects from these alkaloids include stress relief, lightening of anxiety, and easing of symptoms related to depression. They also help to increase mental focus and improve concentration. Most Kratom users notice sensations of euphoria, joy, and optimism as well. Important physical effects include muscle relaxation, pain relief, low blood pressure, and the easing of arthritis symptoms, scoliosis, Fibromyalgia, and carpel tunnel syndrome.

There have been several negative attacks on Kratom in the media, specifically for its particular alkaloids but there have been many tests done that prove Kratom and its alkaloid’s to be harmless.  It is simply another saving grace sent from nature to us!